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Objective:To analyze the epidemiological and clinical characteristics of patients with corona virus disease 2019 (COVID-2019) in Shenyang City.Methods:The epidemiological and clinical characteristics of 30 patients diagnosed with COVID-2019 admitted to Shenyang Sixth People′s Hospital from January 22 to February 8, 2020 were retrospectively analyzed. The independent t test, Mann-Whitney test and Fisher′s exact test were used for statistical analysis. Results:Among the 30 cases, 21 were imported, including 17 from Hubei Province and four from other provinces. Nine cases were local infections. There were 18 men and 12 women, aging from 21 to 72 years with the median of 43 years. Eight cases had underlying diseases including hypertension, diabetes, coronary heart disease and bronchitis. On admission, two (7%) cases were mild, 19(63%) cases were ordinary, eight (27%) cases were severe, and one (3%) case was critical. Clinical manifestations mainly included fever, with or without upper respiratory tract symptoms, normal, decreased or slightly increased white blood cell counts, mainly decreased lymphocyte counts, normal or increased C reactive protein, and normal procalcitonin. The computed tomography (CT) of the early stage of the lungs showed that multiple patchy ground glass shadows were mainly accompanied by consolidation, which often involved both lungs or multiple lobes of one lung. At the moment, the clinical treatment mainly included respiratory support, symptomatic treatment, antiviral treatment and anti-bacterial treatment. By February 15, a total of nine cases were cured and discharged, including one mild case, six ordinary cases, and two severe cases. In the comparisons between mild/ordinary patients and severe/critical patients, the fever duration in the severe/critical group (median 11.5 d) was significantly longer than that in the mild/ordinary group (median 2.0 d) ( Z=-2.292, P=0.022), and the laboratory tests indicated more cases with elevated D-dimer levels ( Z=-2.669, P=0.008) and neutrophilic/lymphocyte ratio >3.0 ( Z=-4.071, P<0.01). Conclusions:In Shenyang City, the early cases with COVID-19 infection are mainly imported cases, and expanding local infections gradually develop. Clinical manifestations are mainly characterized by fever and cough. Lung CT imagings show multiple ground glass shadows, mainly accompanied by consolidation. CT changes in the lungs should be closely monitored during the treatment, and CT findings in the lungs may change earlier than the clinical manifestations. Prolonged fever duration, elevated D-dimer level and neutrophil/lymphocyte ratio >3.0 could be used as early warning indicators for severe cases.
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Objective@#To analyze the epidemiological and clinical characteristics of patients with 2019 novel coronavirus (2019-nCoV) infection in Shenyang.@*Methods@#The epidemiological and clinical characteristics of 30 patients diagnosed with 2019-nCoV infection admitted to Shenyang sixth people's hospital on January 22, 2020 and February 8, 2020 were retrospectively analyzed.@*Results@#Among the 30 cases, 21 were imported, including 17 from Hubei Province and four from other provinces. Nine cases were local infections. There were 18 men and 12 women, aging from 21 to 72 years with the median of 43 years. Eight cases had underlying diseases including hypertension, diabetes, coronary heart disease and bronchitis. On admission, two (7%) cases were mild, 19 (63%) cases were ordinary, eight (27%) cases were severe, and one (3%) case was critical. Clinical manifestations mainly include fever, with or without upper respiratory tract symptoms, normal, decreased or slightly increased white blood cell counts, mainly decreased lymphocyte counts, normal or increased c-reactive protein, and normal procalcitonin. The computed tomography (CT) of the early stage of the lungs showed that multiple patchy ground glass shadows were mainly accompanied by consolidation, which often involved both lungs or multiple lobes of one lung. At the moment, the clinical treatment mainly included respiratory support, symptomatic treatment, antiviral treatment adn anti-bacterial treatment. By February 15, a total of nine cases were cured and discharged, including one mild case, six ordinary cases, and two severe cases. In the comparisons between mild/ordinary patients and severe/critical patients, the fever duration in the severe/critical group (median 11.5 d) was significantly longer than that in the light/normal group (median 2 d) (Z=-2.292, P=0.022), and the laboratory tests indicated elevated d-dimer levels (Z=-2.669, P=0.008) and more cases with neutrophilic/lymphocyte ratio > 3 (Z=-4.071, P<0.01).@*Conclusions@#In Shenyang, the early cases with 2019-nCoV infection are mainly imported cases, and expanding local infections gradually develop. Clinical manifestations are mainly characterized by fever and cough. Lung CT performance shows multiple ground glass shadows, mainly accompanied by consolidation. CT changes in the lungs should be closely monitored during the treatment, and CT findings in the lungs may change earlier than the clinical manifestations. Prolonged fever duration, elevated d-dimer level and neutrophil/lymphocyte ratio >3 could be used as early warning indicators for severe cases.
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Objective To explore the risk factors and interventional strategies of bleeding caused by brain arteriovenous malformations associated with aneurysms.Methods Clinical and imaging data of 42 cases of brain arteriovenous malformations associated with aneurysms were collected and analyzed.According to the results of intraoperative angiography and the architectural characteristics of vessels,the therapeutic schedule was formulated.Three months,6 months and 1 year after interventional management,all patients were followed with DSA to observe whether arteriovenous malformations recurred or not.Results The risk factors of hemorrhage caused by brain arteriovenous malformations associated with aneurysms included lesions located in subtentorium,deep vein or mixed venous drainage,Spetzler-Martin grade Ⅲ-Ⅳ,as well as type Ⅰ and type Ⅱ a aneurysms of Redekop classification.Glasgow outcome score of 38 postoperative patients were more than 4 points,visual impaired happened in 1 patient,whereas 2 patients had different degree of limb dysfunction and 1 patient died.DSA follow-up found no recurrence of arteriovenous malformation in 37 patients.Conclusion Understanding the vessel architectural characteristics and substantial hemorrhage risk factors before intervention,therefore formulating individualized therapeutic schedules are benefit to improving safety and efficacy for the treatment of brain arteriovenous malformations associated with aneurysms.
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Objective To analyze risk factors of hemorrhagic brain arteriovenous malformation (BAVM).Methods Totally 105 BAVM patients confirmed with DSA were collected,and corresponding risk factors were analyzed.Results Univariate analysis suggested that factors were correlated to hemorrhagic presentation including the site and size of the lesions,the type and number of feeding arteries,the number,type and form of draining veins and co-existing arteriovenous fistula.Multiple factors Logistic analysis showed that the location,size,the type and amount of supplying arteries,the number of the draining vein and combined with arteriovenous fistula were the risk factors for hemorrhagic presentation,and drainage vein dilation might be a protective factor.Conclusion Infratentorial and deep cerebral lesions,arteriovenous malformation with diameter ＜3 cm,single draining vein,pure perforating artery,multiple feeding arteries and combined with arteriovenous fistula are risk factors for hemorrhagic BAVM.
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BACKGROUND: Micro-arc oxidation, also be known as micro-plasma oxidation or anodic spark deposition, is a new technology that can in situ grow ceramic coating directly on the surface of non-ferrous metals. And the ceramic coating has such characteristics as high corrosion resistance, good wear resistance, etc. It is advantageous to the osseointegration between implant and bone that the ceramic coating is able to produce porous, rough oxide film on the surface layer of the implant, which improves the biological reaction of the bone interface so as to affect the number of bone-forming cells, ype, products of cell, and the expression of the product.OBJECTIVE: To observe the osseointegration between bone and implant, and to analyze induced action of metal trace elements to bone-formation's marker (ALP). METHODS: A computer-based online search was conducted in PUMMED and Chinese Journal Full-text Database with the key words of "micro-arc oxidation, synosteosis, titanium, magnesium" in both English and Chinese between 1995 and 2009. Additionally, hand-made retrieval was performed for articles about micro-arc oxidation and microelement. Among 96 articles, 34 references were excluded due to unrelated and duplicated articles, and 28 ones were excluded due to long-term publication, 34 ones were included in the final analysis.RESULTS AND CONCLUSION: It is believed that the surface modification methods on microelement and micro-arc oxidation ceramic coating on Ti-based implant will become the mainstream process to improve the rate of implant-bone integration.However, the clinical application still needs to be further studied.
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[Objective]To evaluate the effect of treatment of unstable intertrochanteric fracture with dynamic condylar screw.[Method]Fifty-six cases of unstable intertrochanteric fractures were treated with typical ORIF (open reduction and internal fixation) with dynamic condylar screw from 2000 to 2004. According to the Evan's classification systems, there were 19 cases of Evan's Ⅲ fracture, 27 cases of Evan's Ⅳ fracture and 10 cases oblique reverse Evan'sⅤ fracture. The average period of follow-up was 10 months (8～15 months).[Result]All cases had union with average union time of 4 months, no coxae inversion, fixation failure and fracture nonunion. The satisfactory rate of function was 89%. [Conclusion]For unstable intertrochanteric fracture,including Evan's Ⅲ, Evan's Ⅳ and oblique reverse Evan'sⅤ fracture, using DCS is a good method to improve the clinical results.
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BACKGROUND: Rehabilitation training after sports injury is of so great importance in the remaining and relieving of exercise ability that the researches in thisfield need to develop.OBJECTIVE: To evaluate the influence of isokinetic training on the functional recovery of knee flexors and extensors and the muscle force around the joint after knee meniscus injuries receiving arthroscopy.DESIGN: Case-control observation SETTING: Department of Police Training, Liaoning Advanced Police Officer School PARTICIPANTS: A total of 20 patients with acute meniscus injury of lateral knee joint were selected from the Department of Surgery, Affiliated Hospital of Dalian Medical University between September 2004 and January 2005. They were randomly divided into experimental group and control group,including 11 cases respectively. METHODS: All the patients were treated with arthroscope operation, additionally the control patients received routine blocking, physiotherapy and massage, etc. To recover the function. From the 2nd to 4th days postoperative, the patients of experimental group began to carry out the functional rehabilitation, and received isokinetic exercise in both knees flexors and extensors with the Cybex-6000 isokinetic dynamometer 3 weeks later.MAIN OUTCOME MEASURES: Peak torque values, total work, torque accelerating energy and average power in both knee flexors and extensors at different angular velocities [60, 120 and 180(°)/s].RESULTS: A total of 22 patients were involved in the result analysis.①After arthroscope operation and isokinetic training, the range of joint movement were extended, and the maximum flexion angle changed from (132±25)° to (158±21)°. There were significant differences before and after training by t test (P ＜ 0.01).②The experimental group had statistical significance compare with control group in the test index at 60, 120 and 180(°)/s(P ＜ 0.05).CONCLUSION: The arthroscope combining with isokinetic training can speed up the rehabilitation after knee meniscus injury, enhance the muscle force around knee joint and maintain the stability of knee joint and motor ability.